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ตุลาคม 9, 2023

No level of alcohol consumption is safe for our health

study alcohol cancer

For example, more participants were aware of the cancer risks from hard liquor and beer than about the risk from wine, with some participants believing wine lowers your cancer risk. “We’ve known about this connection for more than 30 years; this is not our first conversation on the topic,” she said. Indeed, WHO’s International Agency for Research on Cancer first classified alcoholic beverages as carcinogenic in 1987. Alcohol causes at least seven types of cancer, including the most common cancer types, such as bowel cancer and female breast cancer.

Alcohol disrupts communication between these organisms and the intestinal immune system. Alcohol consumption also damages epithelial cells, T cells, and neutrophils in the GI system, disrupting gut barrier function and facilitating leakage of microbes into the circulation (see the article by Hammer and colleagues). Reducing or eliminating alcohol intake can lower the risk, offering a form of empowerment in the face of an often unpredictable disease. Alcohol is causally linked to many cancer types, but trends in alcohol consumption patterns change over time and between geographic regions. Therefore, new studies are needed to quantify the contribution of alcohol to the current global burden of cancer.

Because cancer risk increases with the amount of ethanol consumed, all alcoholic beverages pose a risk. Taken together, if these gaps are filled, they could potentially change what we say about the effects of alcohol on cancer risk, how we communicate that evidence and affect drinking behaviors,” she said. Department of Agriculture have defined moderate drinking as no more than one drink per day for women and no more than two drinks per day for men. Researchers have known about the relationship between heavy alcohol consumption and the risk for esophageal and other upper How to Get Sober and What to Expect digestive and respiratory tract cancers since the beginning of the last century. Furthermore, substantial epidemiological evidence (as reviewed in this article) accrued over the past 50 years has shown that alcohol contributes to the development of these cancers.

Shots – Health News

Researchers meticulously measured participants’ finger lengths using calipers and assessed their alcohol consumption patterns using the Alcohol Use Disorders Identification Test (AUDIT), a standardized questionnaire developed by the World Health Organization. In a fascinating new study that bridges anatomy and behavior, researchers have uncovered an unexpected connection between our fingers and our drinking habits. The research, published in the American Journal of Human Biology, suggests that the length ratio between your index and ring fingers might predict how much alcohol you’re likely to consume. In most cases, even if delayed, researchers reported continuing with their public health work. Although less frequent, very serious forms of intimidation were also reported across the sectors. We found reports of surveillance, where researchers and advocates and their families were followed, and cyberattacks where computers and mobile phones were hacked.

  1. To control for this possibility, the investigators included separate analyses for men and women in their statistical models, where feasible.
  2. When the COVID-19 pandemic forced much of the world to shut down, and many days seemed bleak, it was easy to joke about the allure of a splash of rum in a morning coffee, or a cold beer at the end of the day.
  3. The study’s authors suggest that the numbers of alcohol-related cancers are probably even higher than these estimates.
  4. Participants in the survey are a nationally representative sample of adults aged 18 and older.
  5. Educating the public about the cancer risk from drinking alcohol, regardless of the beverage type, is especially urgent given the increase in drinking during the COVID-19 pandemic, Dr. Klein said.

The curves shown here were obtained by fitting certain statistical models to the data from several studies (i.e., a meta-analysis). Blue dotted lines indicate 95-percent confidence intervals; that is, the range of RR that is 95 percent likely to show a true RR. As with other meta-analyses of published studies, the analysis presented here has various limitations and strengths. One limitation is that for most types of cancer included, the estimates of alcohol’s effects tended to vary widely among the individual studies, making interpretation of the pooled data more difficult. Part of this variability may result from differences in the characteristics of the subjects included in the studies.

study alcohol cancer

Cancer Research CatalystThe Official Blog of the American Association for Cancer Research

Recent analyses have revealed flaws in past conclusions that light or moderate alcohol consumption may have heart health benefits. Those studies, scientists say, didn’t adequately account for people who had quit drinking due to health problems. Newer studies are increasingly pointing toward alcohol use as a major cancer risk factor. The CDC reports that more than half of U.S. adults drink alcohol, 17% binge drink, and 6% drink heavily.

Can people’s genes affect their risk of alcohol-related cancers?

The significantly greater risks seen in men carrying the low-alcohol tolerability ALDH2 gene variant who still drank regularly suggests that greater accumulation of acetaldehyde may directly increase cancer risk. The results remained the same when the data were adjusted for other cancer risk factors, such as smoking, diet, physical activity, body mass and family history of cancer. The study team used DNA samples from approximately 150,000 participants (roughly 60,000 men and 90,000 women) in the China Kadoorie Biobank study and measured the frequency of the low-alcohol tolerability alleles for ALDH2 and ADH1B. The data were combined with questionnaires about drinking habits completed by participants at recruitment and subsequent follow-up visits. The participants were tracked for a median period of 11 years through linkage to health insurance records and death registers. To address these unknowns, researchers from Oxford Population Health, Peking University and the Chinese Academy of Medical Sciences, Beijing, used a genetic approach by investigating gene variants linked to lower alcohol consumption in Asian populations.

We found widespread intimidation across the three sectors, perpetrated by corporations themselves and their third parties. Many will be too scared to publicly reveal that they have been intimidated because of their work. Professor Nancy Ip discusses her groundbreaking neuroscience research, focusing on neurotrophic factors and innovative Alzheimer’s disease treatment approaches. Ijeoma Uchegbu discusses nanomedicine’s role in improving medication adherence and developing non-addictive pain relief solutions at ELRIG Drug Discovery 2024.

She agrees with the authors that the results are, if anything, an understatement of the impact of alcohol on cancer cases. And she has suggestions to reduce the burden of alcohol-related cancers that go beyond governmental action. On the other hand, economic growth in places like China, India and Vietnam might lead to increased alcohol use and related cancers down the road.